Diffuse Low-Grade Gliomas in Adults: Natural History, by Hugues Duffau MD, PhD (auth.), Hugues Duffau (eds.)

By Hugues Duffau MD, PhD (auth.), Hugues Duffau (eds.)

This e-book provides the newest learn relating the prognosis, remedy and administration of diffuse low-grade gliomas (DLGG) in adults, with a selected specialize in the trail in the direction of individualised remedy for this type of tumour. contemporary examine at the common heritage of DLGGs and their interplay with the mind has ended in new diagnostic and healing concepts which bring up survival and caliber of lifetime of the sufferer, and those equipment are defined during this book.

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Additional info for Diffuse Low-Grade Gliomas in Adults: Natural History, Interaction with the Brain, and New Individualized Therapeutic Strategies

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Mandonnet E, Pallud J, Fontaine D, Taillandier L, Bauchet L, Peruzzi P, et al. Inter- and intrapatients comparison of WHO grade II glioma kinetics before and after surgical resection. Neurosurg Rev. 2010;33:91–6. 2 Epidemiology of Diffuse Low-Grade Gliomas 49. Bauman G, Lote K, Larson D, Stalpers L, Leighton C, Fisher B, et al. Pretreatment factors predict overall survival for patients with low-grade glioma: a recursive partitioning analysis. Int J Radiat Oncol Biol Phys. 1999;45:923–9. 50. Chang EF, Smith JS, Chang SM, Lamborn KR, Prados MD, Butowski N, et al.

11. Bauchet L, Rigau V, Mathieu-Daudé H, FigarellaBranger D, Hugues D, Palusseau L, et al. French brain tumor data bank: methodology and first results on 10,000 cases. J Neurooncol. 2007;84:189–99. 12. Bauchet L, Rigau V, Mathieu-Daudé H, FabbroPeray P, Palenzuela G, Figarella-Branger D, et al. Clinical epidemiology for childhood primary central nervous system tumors. J Neurooncol. 2009; 92:87–98. 13. Wöhrer A, Waldhör T, Heinzl H, Hackl M, Feichtinger J, Gruber-Mösenbacher U, et al. The Austrian Brain Tumour Registry: a cooperative way to establish a population-based brain tumour registry.

In future, early detection of DLGG could be performed by three different ways, at least. First, MRI is an easy exam considered without risk. Abnormality of signal on FLAIR or T2-weighted images is easy to detect in fast exams. Combining screening of some neurological illness and/or neurovascular illness by MRI could be a realistic first approach. Then, multimodal MRI and consecutive MRIs have good diagnostic power and may suggest specific treatments and/or follow-up. Secondly, if progress in knowledge of risk factors of DLGG occurs, it will be possible to define groups of patients with increase of risk of DLGG.

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