Epistemology of the Cell: A Systems Perspective on by Edward R. Dougherty

By Edward R. Dougherty

"Honorable point out – Biomedicine and Neuroscience, 2011 Prose Awards"

An exam of ways the mobile may be defined that allows you to successfully approach organic data

"The fruitful pursuit of organic wisdom calls for one to take Einstein's admonition [on technological know-how with no epistemology] as a pragmatic call for for medical examine, to acknowledge Waddington's characterization of the subject material of biology, and to include Wiener's belief of the shape of organic wisdom in accordance with its subject material. it truly is from this vantage aspect that we contemplate the epistemology of the cell."
from the Preface

In the period of excessive organic facts throughput, biomedical engineers want a extra systematic wisdom of the cellphone as a way to practice greater info dealing with. Epistemology of the Cell is the 1st authored booklet to collapse this information. this article examines where of organic wisdom in the framework of technological know-how as a complete and addresses concerns all for the categorical nature of biology, how biology is studied, and the way organic wisdom is translated into functions, particularly with reference to medicine.

The booklet opens with a normal dialogue of the old improvement of human figuring out of medical wisdom, the medical process, and the style during which medical wisdom is represented in arithmetic. The narrative then will get particular for biology, concentrating on wisdom of the phone, the fundamental unit of lifestyles. The salient aspect is the analogy among a systems-based research of manufacturing facility rules and the legislation of the mobilephone. each one bankruptcy represents a key subject of present curiosity, including:

  • Causality and randomness

  • Translational science

  • Stochastic validation: classification

  • Stochastic validation: networks

  • Model-based experimentation in biology

Epistemology of the Cell is written for biomedical researchers whose pursuits contain bioinformatics, organic modeling, biostatistics, and organic sign processing.

Show description

Read Online or Download Epistemology of the Cell: A Systems Perspective on Biological Knowledge (IEEE Press Series on Biomedical Engineering) PDF

Best stochastic modeling books

Dynamics of Stochastic Systems

Fluctuating parameters seem in various actual platforms and phenomena. they often come both as random forces/sources, or advecting velocities, or media (material) parameters, like refraction index, conductivity, diffusivity, and so on. the well-known instance of Brownian particle suspended in fluid and subjected to random molecular bombardment laid the basis for contemporary stochastic calculus and statistical physics.

Random Fields on the Sphere: Representation, Limit Theorems and Cosmological Applications (London Mathematical Society Lecture Note Series)

Random Fields at the Sphere provides a complete research of isotropic round random fields. the most emphasis is on instruments from harmonic research, starting with the illustration conception for the gang of rotations SO(3). Many contemporary advancements at the approach to moments and cumulants for the research of Gaussian subordinated fields are reviewed.

Stochastic Approximation Algorithms and Applicatons (Applications of Mathematics)

Lately, algorithms of the stochastic approximation kind have chanced on functions in new and numerous components and new ideas were constructed for proofs of convergence and cost of convergence. the particular and capability functions in sign processing have exploded. New demanding situations have arisen in functions to adaptive keep watch over.

An Introduction to the Analysis of Paths on a Riemannian Manifold (Mathematical Surveys and Monographs)

This e-book goals to bridge the distance among chance and differential geometry. It offers buildings of Brownian movement on a Riemannian manifold: an extrinsic one the place the manifold is learned as an embedded submanifold of Euclidean house and an intrinsic one according to the "rolling" map. it truly is then proven how geometric amounts (such as curvature) are mirrored by means of the habit of Brownian paths and the way that habit can be utilized to extract information regarding geometric amounts.

Extra info for Epistemology of the Cell: A Systems Perspective on Biological Knowledge (IEEE Press Series on Biomedical Engineering)

Example text

Indd 21 6/16/2011 1:59:59 PM 22 Epistemology of the Cell: Perspective on Biological Knowledge connexion between them; some power in the one, by which it infallibly produces the other, and operates with the greatest certainty and strongest necessity. (Hume, 1952) But do repeated conjoined observations warrant the supposition of a necessary connection? Is there a ground in reason or a physical ground for judging there to be a necessary connection? Hume states emphatically that there is no such ground.

Regarding causality, Bertrand Russell states, In the motions of mutually gravitating bodies, there is nothing that can be called a cause, and nothing that can be called an effect; there is merely a formula. Certain differential equations can be found, which hold at every instant for every particle of the system, and which, given the configuration and velocities at one instant, or the configurations at two instants, render the configuration at any other earlier or later instant theoretically calculable.

As a subject of science, human behavior is determined, but only as a subject of science. While Kant no doubt had the intent of establishing the possibility of metaphysics, this does not mean that he did not hit upon a third key point: Science is a product of the human mind and, because science is limited by its epistemology, the mind is only bound to the conclusions of science when it operates within the categories of the understanding, which themselves are limited to phenomenal experience and therefore are not operative outside the domain of that experience.

Download PDF sample

Rated 4.90 of 5 – based on 32 votes