Merkel Cell Carcinoma by Stephen M. Ostrowski, Stephen Michael Maricich (auth.),

By Stephen M. Ostrowski, Stephen Michael Maricich (auth.), Murad Alam, Jeremy S. Bordeaux, Siegrid S. Yu (eds.)

Merkel telephone Carcinoma is without doubt one of the first complete, single-source medical texts at the topic. even though now not as universal as cancer, Merkel cellphone carcinoma isn't really infrequent – and it truly is either extra lethal than cancer and extending at a deadly disease expense. The e-book is scientific in concentration and emphasizes therapy of this poorly understood melanoma. Contributing authors comprise dermatologists, surgical oncologists, radiation oncologists, and scientific oncologists from the united states and round the world.


· complete single-source scientific reference

· therapy concentration

· Written for practitioners, with emphasis on medical relevance and fast retrieval of data

· Contributing authors signify all disciplines keen on remedy of Merkel telephone carcinoma: dermatology, surgical oncology, radiation oncology, and clinical oncology

· foreign in point of view, with individuals from US and overseas

· contributors of energetic Merkel mobile Carcinoma Multicenter curiosity workforce have authored a few of the chapters

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Merkel Cell Carcinoma

Merkel mobilephone Carcinoma is among the first entire, single-source scientific texts at the topic. even if now not as universal as cancer, Merkel cellphone carcinoma isn't really infrequent – and it truly is either extra lethal than cancer and lengthening at a deadly disease fee. The publication is medical in concentration and emphasizes remedy of this poorly understood melanoma.

Additional resources for Merkel Cell Carcinoma

Sample text

Garneski KM et al. Merkel cell polyomavirus is more frequently present in North American than Australian Merkel cell carcinoma tumors. J Invest Dermatol. 2009;129:246–8. Shuda M et al. Human Merkel cell polyomavirus infection I. MCV T antigen expression in Merkel cell carcinoma, lymphoid tissues and lymphoid tumors. Int J Cancer. 2009;125:1243–9. Reisinger DM, Shiffer JD, Cognetta AB, Chang Y, Moore PS. Lack of evidence for basal or squamous cell carcinoma infection with Merkel cell polyomavirus in immunocompetent patients with Merkel cell carcinoma.

Tucci MG et al. Immunohistochemical study of apoptosis markers and involvement of chemokine CXCR4 in skin Merkel cell carcinoma. J Eur Acad Dermatol Venereol. 2006;20:1220–5. Giono LE, Manfredi JJ. The p53 tumor suppressor participates in multiple cell cycle checkpoints. J Cell Physiol. 2006;209:13–20. Vogelstein B, Lane D, Levine AJ. Surfing the p53 network. Nature. 2000;408:307–10. Donehower LA et al. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature.

78. Allen PJ et al. Merkel cell carcinoma: prognosis and treatment of patients from a single institution. J Clin Oncol. 2005;23:2300–9. 79. Ziprin P, Smith S, Salerno G, Rosin RD. Two cases of Merkel cell tumour arising in patients with chronic 80. 81. 82. 83. 84. 85. 86. 87. 88. 89. 90. 91. 92. 93. 94. 95. lymphocytic leukaemia. Br J Dermatol. 2000;142: 525–8. Engels EA, Frisch M, Goedert JJ, Biggar RJ, Miller RW. Merkel cell carcinoma and HIV infection. Lancet. 2002;359:497–8. Penn I, First MR.

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