Ovarian Cancer: Second Edition by Anna Hoekstra, Gustavo C. Rodriguez (auth.), M. Sharon

By Anna Hoekstra, Gustavo C. Rodriguez (auth.), M. Sharon Stack, David A. Fishman (eds.)

Ovarian carcinoma remains to be liable for extra deaths than all different gynecologic malignancies mixed, as a result of a persevered lack of ability to accomplish detection of early (rather than complicated) level illness and the inability of potent tumor-specific therapeutics.

Ovarian carcinogenesis, invasion, and metastatic dissemination require a posh cascade of interrelated genetic, molecular, and biochemical occasions that control the neoplastic transition of standard ovarian floor epithelium.

This moment variation comprises fascinating new advances in ovarian melanoma detection and remedy and gives an research of present study into elements of malignant transformation, progress keep an eye on, and metastasis. A extra distinct realizing of those approaches may perhaps finally translate into the improvement of novel methods for the detection and regulate of ovarian cancer.

"Ovarian melanoma prevention, detection and remedy stay an important well-being care problem. during this textual content notion leaders within the box handle the severe biologic and scientific concerns suitable to the ailment. A entire spectrum of subject matters is roofed delivering modern info on medical discoveries and administration considerations."

Steven T. Rosen, M.D.

Show description

Read Online or Download Ovarian Cancer: Second Edition PDF

Best nonfiction_9 books

Mechanisms and Consequences of Proton Transport

This quantity represents the complaints of the ninth foreign Proton delivery convention, "Mechanisms and effects of Proton delivery" held in Leura, Australia, August 19 -21, two hundred I. This convention has been held for the reason that 1971 each three to four years with few exceptions in organization with the Congress of the overseas Union of Physiological Sciences.

Vertebrate Myogenesis

The improvement of vertebrate muscle has lengthy been an important region of study in developmental biology. over the past decade, novel technical ways have allowed us to resolve to a wide quantity the mechanisms underlying muscle formation, and myogenesis has develop into one of many best-understood paradigms for mobile differentiation.

Crustacean Farming: Ranching and Culture, Second Edition

Crustacean Farming: Ranching and tradition, moment variation. John F. Wickins and Daniel O'C Lee. the second one variation of a very well-received e-book, Crustacean Farming, bargains with all cultivated crustaceans of business value, shrimp, prawns, crayfish, lobsters, crabs, and spiny lobsters, and examines the standards wherein either the feasibility and desirability of farming proposals are assessed.

Merkel Cell Carcinoma

Merkel phone Carcinoma is without doubt one of the first entire, single-source scientific texts at the topic. even supposing now not as universal as cancer, Merkel mobilephone carcinoma isn't really infrequent – and it really is either extra lethal than cancer and lengthening at a deadly disease cost. The booklet is medical in concentration and emphasizes remedy of this poorly understood melanoma.

Additional resources for Ovarian Cancer: Second Edition

Example text

Thus, mutations in the ras oncogene are rare in chicken ovarian cancers, similar to that in human ovarian cancers. 6%) demonstrated significant HER-2/neu staining, and significant expression of HER-2/neu was associated with the larger ovarian tumors, suggesting that it may be a marker of cancer aggressiveness in the chicken. 196,197 Clearly, the chicken, like any other animal model, is far removed from humans and thus suffers from this great limitation. Nonetheless, the clinical and genetic findings in the chicken model bear a resemblance to that in human ovarian carcinomas, thereby providing support for the chicken ovarian cancer animal model.

107. Berube S, Diorio C, Verhoek-Oftedahl W, Brisson J. Vitamin D, calcium, and mammographic breast densities. Cancer Epidemiol Biomarkers Prev. 2004;13(9): 1466–1472. 108. Feskanich D, Ma J, Fuchs CS, et al. Plasma vitamin D metabolites and risk of colorectal cancer in women. Cancer Epidemiol Biomarkers Prev. 2004;13(9):1502–1508. 1 Chemoprevention of Ovarian Cancer 31 109. Garland CF, Garland FC, Gorham ED, et al. The role of vitamin D in cancer prevention. Am J Public Health. 2006;96(2):252–261.

C. Rodriguez implications for prostate cancer chemoprevention by vitamin D. Carcinogenesis. 2004;25(6):967–971. 90. Zehnder D, Bland R, Walker EA, et al. Expression of 25-hydroxyvitamin D3-1alphahydroxylase in the human kidney. J Am Soc Nephrol. 1999;10(12):2465–2473. 91. Zehnder D, Bland R, Williams MC, et al. Extrarenal expression of 25-hydroxyvitamin d(3)-1 alpha-hydroxylase. J Clin Endocrinol Metab. 2001;86(2):888–894. 92. Bouillon R. Vitamin D: from photosynthesis, metabolism, and action to clinical applications.

Download PDF sample

Rated 4.02 of 5 – based on 15 votes